Alanine/serine/cysteine/threonine transporter 1, ASCT-1, ASCT1, AW045657, Glutamate/neutral amino acid transporter, Neutral amino acid transporter A, OTTHUMP00000159933, OTTHUMP00000235138, SATT, SATT_HUMAN, SLC1A4, Solute carrier family 1 (glutamate/neutral amino acid transporter), member 4, Solute carrier family 1 member 4,
SLC1A4, also known as ASCT1, is a neutral amino acid transporter. Its other name, ASCT1, was given because it mediates obligatory exchange of alanine, serine, cysteine, and threonine (1). SLC1A4 mediates the efflux of glutamate from the neuron into the synaptic junction via calcium-independent release, as well as mediating the efflux of L-serine from glial cells and its uptake by neurons (2). SLC1A4-mediated transport is shown to involve a symmetrical potassium-independent electroneutral exchange of neutral amino acids and sodium, such that the current activated during transport is carried only by chloride ions (3).
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
WB: 1:500~1:2000 IHC: 1:50~1:200
Application Notes:
SLC1A4 polyclonal antibody detects endogenous levels of SLC1A4 protein.
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