The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activate
This antibody detects endogenous levels of JNK1 protein only when phosphorylated at Thr183. This antibody also recognizes JNK2 and JNK3 when phosphorylated at the corresponding residues.
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