Chk2 polyclonal antibody, Unconjugated, Rabbit

Catalog Number: BWT-BZ16661
Article Name: Chk2 polyclonal antibody, Unconjugated, Rabbit
Biozol Catalog Number: BWT-BZ16661
Supplier Catalog Number: BZ16661
Alternative Catalog Number: BWT-BZ16661-50UL,BWT-BZ16661-100UL
Manufacturer: Bioworld Technology
Host: Rabbit
Category: Antikörper
Application: ICC, IHC-P, IP, WB
Species Reactivity: Human
Immunogen: A synthesized peptide derived from human Chk2
Conjugation: Unconjugated
Alternative Names: CHEK2, CDS1, CHK2, RAD53, Serine/threonine-protein kinase Chk2, CHK2 checkpoint homolog, Cds1 homolog, Hucds1, hCds1, Checkpoint kinase 2
These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.
Molecular Weight: Calculated MW: 61 kDa, Observed MW: 61 kDa
UniProt: O96017
Purity: Affinity Purified
Form: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application Dilute: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Application Notes: IgG