Axin 2 polyclonal antibody, Unconjugated, Rabbit

Product Overview

• Article Name: Axin 2 polyclonal antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BWT-BZ16795
• Supplier Catalog Number: BZ16795
• Alternative Catalog Number: BWT-BZ16795-50UL,BWT-BZ16795-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: ICC, IHC-P, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: A synthesized peptide derived from human Axin2
• Conjugation: Unconjugated
• Alternative Names: Axil, Axin like protein, Axin2, Axis inhibition protein 2, Conductin

Product Description

Axin1 (Axis inhibition protein 1) and Axin2 are multidomain scaffold proteins that negatively regulate Wnt signaling. Axin1 interacts with APC, GSK-3beta, Dvl, and beta-catenin and promotes the GSK-3beta-mediated phosphorylation and subsequent degradation of beta-catenin .Down-regulates beta-catenin.

Product Properties

• Molecular Weight: Calculated MW: 94 kDa, Observed MW: 94 kDa
• UniProt: Q9Y2T1
• Purity: Affinity Purified
• Form: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application Notes

• Application Dilute: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
• Application Notes: IgG