FADD polyclonal antibody, Unconjugated, Rabbit
Catalog Number:
BWT-BZ16883
Product Overview
Article Name:
FADD polyclonal antibody, Unconjugated, Rabbit
Biozol Catalog Number:
BWT-BZ16883
Supplier Catalog Number:
BZ16883
Alternative Catalog Number:
BWT-BZ16883-50UL,BWT-BZ16883-100UL
Manufacturer:
Bioworld Technology
Host:
Rabbit
Category:
Antikörper
Application:
FC, IHC-P, WB
Species Reactivity:
Mouse
Immunogen:
A synthesized peptide derived from mouse FADD
Conjugation:
Unconjugated
Alternative Names:
FADD protein, GIG3, Growth inhibiting gene 3 protein, Mediator of receptor induced toxicity, MORT1
Product Description
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
Product Properties
Molecular Weight:
Calculated MW: 23 kDa, Observed MW: 28 kDa
UniProt:
Q61160
Purity:
Affinity Purified
Form:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application Notes
Application Dilute:
WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100
Application Notes:
IgG
