Integrin beta 4 polyclonal antibody, Unconjugated, Rabbit

Product Overview

• Article Name: Integrin beta 4 polyclonal antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BWT-BZ17003
• Supplier Catalog Number: BZ17003
• Alternative Catalog Number: BWT-BZ17003-50UL,BWT-BZ17003-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: IHC-P, WB
• Species Reactivity: Human
• Immunogen: Recombinant protein of mouse Integrin beta 4
• Conjugation: Unconjugated
• Alternative Names: CD104

Product Description

Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling.

Product Properties

• Molecular Weight: Calculated MW: 202 kDa, Observed MW: 202 kDa
• UniProt: A2A863
• Purity: Affinity Purified
• Form: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application Notes

• Application Dilute: WB: 1/500-1/1000 IHC: 1/50-1/100
• Application Notes: IgG