Endonuclease G polyclonal antibody, Unconjugated, Rabbit
Biozol Catalog Number:
BWT-CAS75127
Supplier Catalog Number:
CAS75127
Alternative Catalog Number:
BWT-CAS75127-50UL,BWT-CAS75127-100UL
Manufacturer:
Bioworld Technology
Host:
Rabbit
Category:
Antikörper
Application:
IHC, IP, WB
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant protein of human Endonuclease G.
Conjugation:
Unconjugated
Alternative Names:
Endonuclease G, mitochondrial , Endo G, ENDOG
Endonuclease G (EndoG) is a nuclear-encoded mitochondrial nuclease that has been reported to function in apoptosis, DNA recombination and cell proliferation. EndoG is expressed as a precursor protein containing an amino-terminal mitochondrial targeting sequence which is removed when the protein is imported into the mitochondria. During apoptosis EndoG is released from the mitochondria, translocates to the nucleus and cooperates with other nucleases to trigger DNA fragmentation associated with the apoptotic process
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.
Application Dilute:
WB: 1:2000~1:5000 IP:1:2000~8000 IHC:1:50~1:100
Application Notes:
Endonuclease G polyclonal antibody detects endogenous levels of Endonuclease G protein.
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