Phospho-Dishevelled 2 (Ser143) monoclonal antibody, Unconjugated, Rabbit

Product Overview

• Article Name: Phospho-Dishevelled 2 (Ser143) monoclonal antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BWT-MB10834
• Supplier Catalog Number: MB10834
• Alternative Catalog Number: BWT-MB10834-50UL,BWT-MB10834-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human, Mouse
• Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser143 of human Dishevelled 2
• Conjugation: Unconjugated
• Alternative Names: DSH homolog 2

Product Description

Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling.

Product Properties

• Molecular Weight: Calculated MW: 79 kDa, Observed MW: 90-95 kDa
• UniProt: O14641
• Purity: Affinity Purified
• Form: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Application Notes

• Application Dilute: WB: 1/500-1/1000
• Application Notes: IgG