MLKL (5E3) monoclonal antibody, Unconjugated, Mouse

Product Overview

• Article Name: MLKL (5E3) monoclonal antibody, Unconjugated, Mouse
• Biozol Catalog Number: BWT-MB3294
• Supplier Catalog Number: MB3294
• Alternative Catalog Number: BWT-MB3294-50UL,BWT-MB3294-100UL
• Manufacturer: Bioworld Technology
• Host: Mouse
• Category: Antikörper
• Application: IHC-P
• Species Reactivity: Human
• Immunogen: Synthetic peptide conjugated to KLH.
• Conjugation: Unconjugated
• Alternative Names: MLKL

Product Description

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

Product Properties

• UniProt: Q8NB16
• Purity: Affinity Purified
• Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application Notes

• Application Dilute: IHC: 1/50-1/100
• Application Notes: IgG1