Recombinant protein expressed in E.coli corresponding to amino acids 1-313 of human CDX2
Conjugation:
Unconjugated
Alternative Names:
CDX-3, CDX2/AS, CDX3
The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear proteins that bind to specific sequences within the promoter of the insulin gene (INS, MIM 176730)and interact with RNA polymerase to activate or repress transcription. The proteins LMX1 (MIM600298) and CDX3 are homeodomain proteins that bind an A/T-rich sequence in the insulin promoter and stimulate its transcription.
The antibody was affinity-purified from mouse ascites fluids or tissue culture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Application Dilute:
WB 1:1000
Application Notes:
IgG2a
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