Angiotensin I converting enzyme 2,Severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, HCoV-19, SARS2, 2019-nCoV, COVID-19, COVID-19 virus, Human coronavirus 2019
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2 (COVID-19 virus).
Rabbit IgG,1mg/ml in PBS with 0.02% sodium azide,10% glycerol, pH7.2
Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Application Dilute:
WB: 1:2000~10000
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