Recombinant Human Fibrobalst Growth Factor-19 (rHuFGF-19)

Product Overview

• Article Name: Recombinant Human Fibrobalst Growth Factor-19 (rHuFGF-19)
• Biozol Catalog Number: BWT-PR1025
• Supplier Catalog Number: PR1025
• Alternative Catalog Number: BWT-PR1025-5UG,BWT-PR1025-25UG,BWT-PR1025-1.0MG
• Manufacturer: Bioworld Technology
• Category: Proteine/Peptide

Product Description

Fibroblast growth factor 19 (FGF19) belongs to the large FGF family which has at least 23 members. All FGF family members are heparin binding growth factors with a core 120 amino acid (aa) FGF domain that allows for a common tertiary structure. FGFs are expressed during embryonic development and in restricted adult tissues. Four distinct but related classes of FGF receptors, FGF R1, 2, 3, and 4, exist. Unlike most FGFs which bind to and activate more than one FGF receptor, FGF19 is a specific ligand for FGF R4.

Product Properties

• Molecular Weight: Approximately 21.8 kDa, a single non-glycosylated polypeptide chain containing 195 amino acids.
• Source: Escherichia coli.
• Purity: >95% by SDS-PAGE and HPLC analyses.
• Form: Sterile Filtered White lyophilized (freeze-dried) powder.
• Sequence: MRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK
• Formula: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.

Application Notes

• Application Notes: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <-20C. Further dilutions should be made in appropriate buffered solutions.