BDTX-189 is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations(KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively). BDTX-189 exhibits anticancer activity.
Molecular Weight:
561
Purity:
>98% (HPLC)
CAS Number:
[2414572-47-5]
Formula:
C29H29ClN6O4
Target:
BLK|EGFR|HER2|RIPK2
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