CU-CPT9b is an antagonist of toll-like receptor 8 (TLR8, Kd = 21 nM). It inhibits activation of NF-kappaB induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM.
Molecular Weight:
251.3
Purity:
>98% (HPLC)
CAS Number:
[2162962-69-6]
Formula:
C16H13NO2
Target:
TLR8
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