Shikonin is an TMEM16A chloride channel inhibitor (IC50: 6.5 µM). Shikonin is also a selective PKM2 inhibitor and can also suppress activation of the NF-kappaB pathway and inhibit TNF-alpha.
Molecular Weight:
288.3
Purity:
>98% (HPLC)
CAS Number:
[517-89-5]
Formula:
C16H16O5
Target:
TMEM16A chloride channel|PKM2|NF-kappaB|TNF-alpha
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