Halofuginone, the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-beta signaling at 10 ng/ml in the mammal.
Molecular Weight:
414.7
Purity:
>98% (HPLC)
CAS Number:
[55837-20-2]
Formula:
C16H17BrClN3O3
Target:
prolyl-tRNA synthetase
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