Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo with IC50 of ~ 1.5 µM in HEK293T cell and also is an inducer of osteoblast differentiation with EC50 of 1 µM.
Molecular Weight:
520.6
Purity:
>98%(HPLC)
CAS Number:
[483367-10-8]
Formula:
C31H32N6O2
Target:
Smoothened
* VAT and and shipping costs not included. Errors and price changes excepted