Tofacitinib (CP-690550) is a potent, specific, orally active inhibitor of JAK3 with IC50 of 1 nM in cell-free assays, displays 20- to 100-fold less potency for JAK2 and JAK1 (IC50=20 nM and 112 nM, respectively).
Molecular Weight:
312.4
Purity:
>98% (HPLC)
CAS Number:
[477600-75-2]
Formula:
C16H20N6O
Target:
JAK1|JAK2|JAK3|Lck|ROCK2
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