A selective CDK2 inhibitor with IC50 of 22 nM, shows less potent for CDK1/CDK4(IC50=40/200 nM), no inhibition on PKC, EGFR, p38MAPK, decreases the phosphorylation of pRb, and increases caspase-3 activation.
Molecular Weight:
241.2
Purity:
>98% (HPLC)
CAS Number:
[377090-84-1]
Formula:
C13H11N3O2
Target:
CDK1|CDK2|CDK4|p38|PKC
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