A small-molecule enhancer/inducer of Autophagy, decreases the levels of Abeta peptide (EC50=10 uM) and APP-CTF (EC50 of 20 uM) in a gamma-secretase-independent manner in primary neuronal cultures, Atg5, Beclin1 and Ulk1 are shown to be involved in the degradation of Abeta and APP-CTF.
Molecular Weight:
264.1
Purity:
>98% (HPLC)
CAS Number:
[307538-42-7]
Formula:
C11H10BrN3
Target:
Autophagy
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