PQR309 (Bimiralisib) is a potent, brain-penetrant, orally bioavailable, pan-class I PI3K/mTOR inhibitor with IC50 of 33, 451, 661, 708 and 89 nM for PI3Kalpha, PI3Kdelta, PI3Kbeta, PI3Kgamma and mTOR, respectively.
Molecular Weight:
411.4
Purity:
>98% (HPLC)
CAS Number:
[1225037-39-7]
Formula:
C17H20F3N7O2
Target:
pPKB|pS6
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