A potent, orally bioavailable Aurora kinases inhibitor with IC50 of 15/25/19 nM for Aurora A/B/C, displays antiproliferative activity in a range of human tumor cell lines, including SW620 colon carcinoma (GI50=0.30 uM) and A2780 ovarian cancer cell line (GI50=0.14 uM).
Molecular Weight:
551.5
Purity:
>98% (HPLC)
CAS Number:
[1095382-05-0]
Formula:
C26H31BrN8O
Target:
AuroraA|AuroraB|AuroraC
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