DEBIO 1143 (AT-406, DEBIO-1143, SM406, ARRY-334543, D1143) is potent, orally active Smac mimetic that antagonizes cIAP1, cIAP2 and XIAP with Ki of 66.4, 1.9 and 5.1 nM, respectively.
Molecular Weight:
561.7
Purity:
>98% (HPLC)
CAS Number:
[1071992-99-8]
Formula:
C32H43N5O4
Target:
cIAP1-BIR3|cIAP2-BIR3|XIAP-BIR3
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