GDC-0980 (Apitolisib, GNE 390, RG 7422) is a potent, selective, orally available class I PI3K/mTOR inhibitor with IC50 of 5 nM/27 nM/7 nM/14 nM for PI3Kalpha/beta/delta/gamma, inhibits mTOR inhibitor with Ki of 17 nM.
Molecular Weight:
498.6
Purity:
>98% (HPLC)
CAS Number:
[1032754-93-0]
Formula:
C23H30N8O3S
Target:
mTOR|p110alpha|p110beta|p110gamma|p110delta
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