SARS-CoV-2 (COVID-19) Spike (D614G) (Stable Trimer) Recombinant Protein

Catalog Number: BYT-ORB1231041
Article Name: SARS-CoV-2 (COVID-19) Spike (D614G) (Stable Trimer) Recombinant Protein
Biozol Catalog Number: BYT-ORB1231041
Supplier Catalog Number: orb1231041
Alternative Catalog Number: BYT-ORB1231041-50
Manufacturer: Biorbyt
Category: Proteine/Peptide
Alternative Names: 2019-nCoV Spike Protein S, covid-19, sars-cov-2
SARS-CoV-2 (COVID-19) Spike (D614G) (Stable Trimer) Recombinant Protein
Concentration: 0.2mg/ml after reconstitution.
Molecular Weight: ~190kDa (SDS-PAGE)
NCBI: 0
UniProt: P0DTC2
Buffer: Lyophilized. Contains PBS and 0.5% trehalose.
Purity: 90% (SDS-PAGE)
Form: Lyophilized
Sequence: Full-length soluble SARS-CoV-2 Spike protein (aa 16-1213) including a foldon trimerization motif, mutated Furin recognition site (R682S, R685S) and two stabilizing mutations (K986P and V987P) is fused at the C-terminus to a His-tag.
Target: S
Application Notes: Biological Activity: Binds to the human SARS-CoV-2 receptor ACE2. Binds to anti-SARS-CoV-2 Spike antibodies in serum or plasma
Full-length trimeric SARS-CoV-2 Spike binds to its receptor ACE2 (human) (rec.) with high affinity.
SDS-PAGE: Coomassie staining under non-reducing conditions, showing one clear band at 190kDa and confirming purity of the protein.
SARS-CoV-2 Spike Protein (D614G) (Stable Trimer) (rec.) (His) migrates by Size Exclusion Chromatography (SEC) as a single peak.