Thapsigargin, CAS [[67526-95-8]]

Product Overview

• Article Name: Thapsigargin, CAS [[67526-95-8]]
• Biozol Catalog Number: BYT-ORB1296066
• Supplier Catalog Number: orb1296066
• Alternative Catalog Number: BYT-ORB1296066-1, BYT-ORB1296066-1
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: unfolded, protein ,response, SARSCoV, SARS coronavirus, SARS-CoV, stress, Thapsigargin, inhibit, Inhibitor, Apoptosis, CalciumChannel, Ca2+ channels, Ca2+-ATPase, Calcium Channel, Ca channels, coronavirus

Product Description

Thapsigargin is a natural SERCA inhibitor that disrupts calcium homeostasis by blocking Ca2+ uptake into the ER/SR, leading to elevated cytosolic Ca2+ and ER stress. It is widely used in vitro and in vivo to study apoptosis, autophagy, and ER stress signaling pathways in cancer and neurodegenerative disease research.

Product Properties

• Molecular Weight: 650.75
• Purity: 99.30% (May vary between batches)
• CAS Number: [67526-95-8]
• Formula: C34H50O12
• Target: Apoptosis,SARS-CoV,Calcium Channel

Application Notes

• Application Notes: Solubility: DMSO:252.5 mg/mL (388.01 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.68 mM)