Olafertinib, CAS [[1660963-42-7]]

Product Overview

• Article Name: Olafertinib, CAS [[1660963-42-7]]
• Biozol Catalog Number: BYT-ORB1296096
• Supplier Catalog Number: orb1296096
• Alternative Catalog Number: BYT-ORB1296096-1, BYT-ORB1296096-1, BYT-ORB1296096-10, BYT-ORB1296096-100, BYT-ORB1296096-25, BYT-ORB1296096-5, BYT-ORB1296096-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: CK 101, CK101, CK-101, EGFR, EGFR (T790M), EGFR-IN-3, Epidermal growth factor receptor, ErbB-1, HER1, Inhibitor, Olafertinib, NSCLC, inhibit, RX 518, RX518, RX-518

Product Description

Olafertinib (RX-518) is an oral, irreversible, and mutant-selective EGFR inhibitor designed to target T790M-mediated resistance in non-small cell lung cancer (NSCLC). It demonstrates potent activity in both cellular assays and in vivo xenograft models, supporting its investigation as a therapeutic agent for EGFR-mutant NSCLC.

Product Properties

• Molecular Weight: 530.57
• Purity: 99.71% (May vary between batches)
• CAS Number: [1660963-42-7]
• Formula: C29H28F2N6O2
• Target: EGFR

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.54 mM),DMSO:120 mg/mL (226.17 mM),H2O:Insoluble