BAR 502, BAR502, BAR-502, Autophagy, G-protein coupled receptor 19, GPBAR1, GPCR19, FXR, G protein-coupled Bile Acid Receptor 1, Inhibitor, NR1H4, inhibit, TGR5
BAR502 is a dual agonist targeting both the GPBAR1 (TGR5) and FXR receptors, with respective IC50 values of 0.4 µM and 2 µM. This small molecule is a valuable research tool for investigating metabolic and inflammatory pathways in both in vitro and in vivo models of liver and intestinal diseases.
Molecular Weight:
392.62
Purity:
99.95% (May vary between batches)
CAS Number:
[1612191-86-2]
Formula:
C25H44O3
Target:
Autophagy,FXR,GPCR19
Application Notes:
Solubility: DMF:48 mg/mL (122.26 mM)
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