CD135, Cluster of differentiation antigen 135, CD117, cKit, c-Kit, AC710, AC-710, AC 710, FLT3, Fms like tyrosine kinase 3, Inhibitor, inhibit, Kit, Platelet-derived growth factor receptor, PDGFR, PDGFRbeta, PDGFRalpha, SCFR
AC710 is a potent small molecule inhibitor targeting PDGFRs, with high affinity for FLT3, KIT, CSF1R, PDGFRalpha, and PDGFRbeta (Kd values 0.6-1.57 nM). It is a valuable research tool for studying receptor tyrosine kinase signaling in oncology and hematology research, applicable in both cellular and animal models.