NVP-CGM097, CAS [[1313363-54-0]]
Catalog Number:
BYT-ORB1296113
Product Overview
Article Name:
NVP-CGM097, CAS [[1313363-54-0]]
Biozol Catalog Number:
BYT-ORB1296113
Supplier Catalog Number:
orb1296113
Alternative Catalog Number:
BYT-ORB1296113-1, BYT-ORB1296113-1, BYT-ORB1296113-10, BYT-ORB1296113-100, BYT-ORB1296113-25, BYT-ORB1296113-5, BYT-ORB1296113-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
Alternative Names:
E1 activating enzyme, E1 Enzyme, E3Enzyme, E1/E2/E3 Enzyme, E1Enzyme, E2 conjugating enzyme, E2 Enzyme, E2Enzyme, E3 Enzyme, E3 ligating enzyme, CGM 097, CGM097, CGM-097, NVP CGM097, NVP-CGM 097, NVPCGM097, NVP-CGM097, NVP-CGM-097, inhibit, Inhibitor, MDM-2/p53, Mdm2, MDM2, Ubiquitin activating enzyme, Ubiquitin conjugating enzyme, Ubiquitin ligase
Product Description
NVP-CGM097 (CGM097) is a potent and selective small-molecule inhibitor of the MDM2-p53 interaction, exhibiting an IC50 of 1.7 nM against human MDM2. It is widely used in cancer research to reactivate p53 pathways, facilitating studies on tumor suppression in both cellular and animal models.
Product Properties
Molecular Weight:
659.26
Purity:
98.92% (May vary between batches)
CAS Number:
[1313363-54-0]
Formula:
C38H47ClN4O4
Target:
E1/E2/E3 Enzyme,Mdm2,MDM-2/p53
Application Notes
Application Notes:
Solubility: DMSO:48 mg/mL (72.81 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.03 mM),H2O:Insoluble