Phorbol 12-myristate 13-acetate, CAS [[16561-29-8]]

Product Overview

• Article Name: Phorbol 12-myristate 13-acetate, CAS [[16561-29-8]]
• Biozol Catalog Number: BYT-ORB1296136
• Supplier Catalog Number: orb1296136
• Alternative Catalog Number: BYT-ORB1296136-1, BYT-ORB1296136-5
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Protein kinase C, S1PReceptor, S1P Receptor, TPA, SphK, Sphingosine kinase, PKC, Phorbol 12 myristate 13 acetate, Phorbol 12-myristate, Phorbol 12myristate 13acetate, Phorbol 12-myristate 13-acetate, Phorbol myristate, Nuclear factor-kappaB, Nuclear factor-kappaB, PMA, NFkappaB, NF-kappaB, NFkB, NF-kB, Inhibitor, inhibit

Product Description

Phorbol 12-myristate 13-acetate (PMA) is a potent cell-permeable activator of protein kinase C (PKC), sphingosine kinase (SphK), and the NF-kappaB pathway. It is widely utilized in research to differentiate monocytic THP-1 cells into macrophages in vitro and to establish inflammatory models, such as dermatitis, in vivo.

Product Properties

• Molecular Weight: 616.83
• Purity: >99.99% (May vary between batches)
• CAS Number: [16561-29-8]
• Formula: C36H56O8
• Target: PKC,NF-kappaB,S1P Receptor

Application Notes

• Application Notes: Solubility: DMSO: 60 mg/mL (97.27 mM), Sonication is recommended. H2O: Insoluble