PAP-1, CAS [[870653-45-5]]

Product Overview

• Article Name: PAP-1, CAS [[870653-45-5]]
• Biozol Catalog Number: BYT-ORB1296152
• Supplier Catalog Number: orb1296152
• Alternative Catalog Number: BYT-ORB1296152-1, BYT-ORB1296152-1, BYT-ORB1296152-10, BYT-ORB1296152-100, BYT-ORB1296152-25, BYT-ORB1296152-5, BYT-ORB1296152-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: 5-(4-Phenoxybutoxy)psoralen, Inhibitor, PAP 1, PAP-1, PAP1, KcsA, Kv1.3 channels, inhibit, Potassium Channel, PotassiumChannel

Product Description

PAP-1 is a potent and selective small molecule inhibitor of the Kv1.3 potassium channel, exhibiting an EC50 of 2 nM and oral bioavailability. Its research applications include in vitro electrophysiology studies and in vivo models for investigating T cell-mediated autoimmune diseases, such as multiple sclerosis and type-1 diabetes.

Product Properties

• Molecular Weight: 350.36
• Purity: 99.75% (May vary between batches)
• CAS Number: [870653-45-5]
• Formula: C21H18O5
• Target: Potassium Channel

Application Notes

• Application Notes: Solubility: DMSO:50 mg/mL (142.71 mM),H2O:Insoluble,10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.71 mM)