Tesevatinib, CAS [[781613-23-8]]

Product Overview

• Article Name: Tesevatinib, CAS [[781613-23-8]]
• Biozol Catalog Number: BYT-ORB1296161
• Supplier Catalog Number: orb1296161
• Alternative Catalog Number: BYT-ORB1296161-1, BYT-ORB1296161-1, BYT-ORB1296161-10, BYT-ORB1296161-2, BYT-ORB1296161-25, BYT-ORB1296161-5, BYT-ORB1296161-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: XL647, XL-647, XL 647, Vascular endothelial growth factor receptor, VEGFR, Tesevatinib, KDR, KD019, KD-019, KD 019, inhibit, Inhibitor, HER2/ErbB2, HER1, FLT4, EXEL7647, EXEL-7647, EXEL 7647, ErbB-1, ErbB2, Ephrin Receptor, EphB4, Epidermal growth factor receptor, EphrinReceptor, EGFR

Product Description

Tesevatinib (XL-647) is an orally bioavailable, multi-targeted tyrosine kinase inhibitor. It potently inhibits EGFR, ErbB2, KDR, Flt4, and EphB4 with low nanomolar IC50 values. This compound has been utilized in preclinical research for studying cancers and angiogenesis in both cellular and animal models.

Product Properties

• Molecular Weight: 491.39
• Purity: 99.99% (May vary between batches)
• CAS Number: [781613-23-8]
• Formula: C24H25Cl2FN4O2
• Target: FLT,Src,VEGFR,Ephrin Receptor,EGFR

Application Notes

• Application Notes: Solubility: DMSO:45 mg/mL (91.58 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.07 mM)