JNJ-40411813 (ADX-71149) is a positive allosteric modulator of the metabotropic glutamate 2 receptor (mGlu2R) with an EC50 of 147 nM. This compound is a valuable research tool for investigating mGlu2R function in neuropsychiatric disorders, facilitating both in vitro binding studies and in vivo behavioral experiments.
Molecular Weight:
344.88
Purity:
99.74% (May vary between batches)
CAS Number:
[1127498-03-6]
Formula:
C20H25ClN2O
Target:
GluR
Application Notes:
Solubility: DMSO:24 mg/mL (69.59 mM)
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