central nervous system dysfunction, Inhibitor, inhibit, LY2795050, LY-2795050, LY 2795050, OpioidReceptor, Opioid Receptor, kappa-opioid receptor, kappakappa-receptor, sex differences
LY2795050 is a potent and selective kappa-opioid receptor (KOR) antagonist with an IC50 of 0.72 nM. This compound is a valuable research tool for investigating KOR function in both in vitro assays and in vivo models related to addiction, pain, and mood disorders.