MI-463, CAS [[1628317-18-9]]

Product Overview

• Article Name: MI-463, CAS [[1628317-18-9]]
• Biozol Catalog Number: BYT-ORB1296237
• Supplier Catalog Number: orb1296237
• Alternative Catalog Number: BYT-ORB1296237-1, BYT-ORB1296237-1, BYT-ORB1296237-10, BYT-ORB1296237-100, BYT-ORB1296237-25, BYT-ORB1296237-5, BYT-ORB1296237-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Inhibitor, Menin-MLL, Histone Methyltransferase, HistoneMethyltransferase, Epigenetic Reader Domain, EpigeneticReaderDomain, inhibit, MI 463, MI463, MI-463

Product Description

MI-463 is a potent, orally bioavailable small molecule inhibitor of the menin-MLL protein-protein interaction, exhibiting an IC50 of 15.3 nM. It is a valuable chemical probe for researching MLL-rearranged leukemias in both cellular assays and in vivo models.

Product Properties

• Molecular Weight: 484.54
• Purity: >99.99% (May vary between batches)
• CAS Number: [1628317-18-9]
• Formula: C24H23F3N6S
• Target: Histone Methyltransferase,Epigenetic Reader Domain

Application Notes

• Application Notes: Solubility: DMSO:120 mg/mL (247.66 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.26 mM)