AMG-3969, CAS [[1361224-53-4]]

Product Overview

• Article Name: AMG-3969, CAS [[1361224-53-4]]
• Biozol Catalog Number: BYT-ORB1296239
• Supplier Catalog Number: orb1296239
• Alternative Catalog Number: BYT-ORB1296239-1, BYT-ORB1296239-1, BYT-ORB1296239-10, BYT-ORB1296239-100, BYT-ORB1296239-200, BYT-ORB1296239-25, BYT-ORB1296239-5, BYT-ORB1296239-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Glucokinase, GK-GKRP, Hexokinase D, Hexokinase IV, Inhibitor, inhibit, AMG 3969, AMG3969, AMG-3969

Product Description

AMG-3969 is a potent small molecule disruptor of the glucokinase-glucokinase regulatory protein (GK-GKRP) interaction, exhibiting an IC50 of 4 nM. This tool compound is valuable for diabetes research, enabling the study of hepatic glucose metabolism in both cellular and animal models to explore potential therapeutic strategies.

Product Properties

• Molecular Weight: 522.46
• Purity: 99.65% (May vary between batches)
• CAS Number: [1361224-53-4]
• Formula: C21H20F6N4O3S
• Target: Glucokinase

Application Notes

• Application Notes: Solubility: DMSO:100 mg/mL (191.4 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.66 mM)