BI-882370, CAS [[1392429-79-6]]

Product Overview

• Article Name: BI-882370, CAS [[1392429-79-6]]
• Biozol Catalog Number: BYT-ORB1296244
• Supplier Catalog Number: orb1296244
• Alternative Catalog Number: BYT-ORB1296244-1, BYT-ORB1296244-10, BYT-ORB1296244-2, BYT-ORB1296244-25, BYT-ORB1296244-5, BYT-ORB1296244-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: C-Raf, B-Raf (V600E), B-Raf, BI882370, BI-882370, BI 882370, inhibit, Inhibitor, Raf kinases, Raf

Product Description

BI-882370 is a potent and selective RAF kinase inhibitor with low nanomolar IC50 values against oncogenic BRAF(V600E), wild-type BRAF, and CRAF. It also exhibits activity against SRC family kinases. This inhibitor is a valuable research tool for studying MAPK pathway signaling in cancers, supporting both in vitro and in vivo preclinical investigations.

Product Properties

• Molecular Weight: 569.67
• Purity: 99.07% (May vary between batches)
• CAS Number: [1392429-79-6]
• Formula: C28H33F2N7O2S
• Target: Raf

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.76 mM),DMSO:5 mg/mL (8.78 mM)