Abrocitinib, CAS [[1622902-68-4]]

Product Overview

• Article Name: Abrocitinib, CAS [[1622902-68-4]]
• Biozol Catalog Number: BYT-ORB1296253
• Supplier Catalog Number: orb1296253
• Alternative Catalog Number: BYT-ORB1296253-1, BYT-ORB1296253-10, BYT-ORB1296253-100, BYT-ORB1296253-2, BYT-ORB1296253-25, BYT-ORB1296253-5, BYT-ORB1296253-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: PF04965842, PF-04965842, PF 04965842, inhibit, JAK1, JAK2, JAK, Janus kinase, Inhibitor, Abrocitinib

Product Description

Abrocitinib (PF-04965842) is a potent and selective oral inhibitor of JAK1, demonstrating high selectivity over JAK2 (IC50s: 29 nM and 803 nM, respectively). It is a valuable research tool for investigating JAK1-mediated pathways in immunological and inflammatory diseases, with utility in both in vitro and in vivo preclinical studies.

Product Properties

• Molecular Weight: 323.41
• Purity: 99.91% (May vary between batches)
• CAS Number: [1622902-68-4]
• Formula: C14H21N5O2S
• Target: JAK

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (12.37 mM),DMSO:125 mg/mL (386.51 mM)