AMG 837 calcium hydrate is a potent and selective GPR40 agonist (EC50 = 13 nM), exhibiting over 1000-fold selectivity against related receptors GPR41, GPR43, and GPR120. This small molecule is a valuable research tool for investigating GPR40s role in glucose homeostasis and insulin secretion in both cellular and animal models of diabetes.
Molecular Weight:
950.97
Purity:
98.96% (May vary between batches)
CAS Number:
[1259389-38-2]
Formula:
C52H44CaF6O8
Target:
GPCR
Application Notes:
Solubility: DMSO:40 mg/mL (42.06 mM)
* VAT and and shipping costs not included. Errors and price changes excepted