HS024 is a potent and selective melanocortin MC4 receptor antagonist with high affinity for the human MC4 receptor (Ki = 0.29 nM). It is utilized in research to study energy homeostasis and cardiovascular regulation, as it increases food intake and blocks alpha-MSH-induced hypotension and bradycardia in rodent models following central administration.
Molecular Weight:
1266.5
Purity:
>99.99% (May vary between batches)
CAS Number:
[212370-59-7]
Formula:
C58H79N19O10S2
Target:
Melanocortin Receptor
Application Notes:
Solubility: H2O:0.5 mg/mL (0.39 mM)
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