DNA Alkylation, DNA alkylator, DNAAlkylation, Methyl methanesulfonate
Methyl methanesulfonate (MMS) is a DNA alkylating agent that primarily methylates adenine and guanine bases, leading to 3-methyladenine and 7-methylguanine lesions. These modifications cause base mispairing and replication blocks, making MMS a valuable tool for studying DNA damage response, repair mechanisms, and genotoxicity in both cellular and animal models.
Molecular Weight:
110.13
Purity:
99.69% (May vary between batches)
CAS Number:
[66-27-3]
Formula:
C2H6O3S
Target:
DNA Alkylator/Crosslinker,Necroptosis,MDM-2/p53,ROS,DNA Alkylation
Application Notes:
Solubility: DMSO:60 mg/mL (544.81 mM)
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