Denosumab is a human monoclonal antibody administered via subcutaneous injection. It functions by binding to and inhibiting RANKL, thereby suppressing osteoclast formation and activity. This mechanism is utilized in research models of osteoporosis, bone metastasis, and rheumatoid arthritis to study bone resorption pathways.
Concentration:
62.5 mg/mL
Molecular Weight:
144.71 kDa
Purity:
99.90% (May vary between batches)
CAS Number:
[615258-40-7]
Formula:
C6404H9912N1724O2004S50
Target:
NF-kappaB,Caspase,Apoptosis,RANKL/RANK
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