Samelisant (SUVN-G3031) is a potent, selective inverse agonist of the histamine H3 receptor, exhibiting Kis of 8.7 nM (human) and 9.8 nM (rat). It demonstrates anticataplectic activity in vivo and is a valuable research tool for investigating narcolepsy and related sleep/wake disorders in both in vitro and in vivo experimental models.
Molecular Weight:
373.49
Purity:
99.59% (May vary between batches)
CAS Number:
[1394808-82-2]
Formula:
C21H31N3O3
Target:
Histamine Receptor
Application Notes:
Solubility: DMSO:50 mg/mL (133.87 mM)
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