DB2313, CAS [[2170606-74-1]]

Product Overview

• Article Name: DB2313, CAS [[2170606-74-1]]
• Biozol Catalog Number: BYT-ORB1297932
• Supplier Catalog Number: orb1297932
• Alternative Catalog Number: BYT-ORB1297932-1, BYT-ORB1297932-10, BYT-ORB1297932-100, BYT-ORB1297932-200, BYT-ORB1297932-25, BYT-ORB1297932-5, BYT-ORB1297932-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: DB2313, DB-2313, DB 2313, Carboximidamide, Apoptosis

Product Description

DB2313 (Carboximidamide) is a potent and selective small molecule inhibitor of the transcription factor PU.1 (IC50=14 nM), disrupting its binding to DNA. It induces apoptosis in acute myeloid leukemia (AML) cells in vitro and has demonstrated anticancer efficacy in preclinical in vivo models, supporting its use in hematological malignancy research.

Product Properties

• Molecular Weight: 708.83
• Purity: 99.73% (May vary between batches)
• CAS Number: [2170606-74-1]
• Formula: C42H41FN8O2
• Target: Apoptosis

Application Notes

• Application Notes: Solubility: DMSO:3 mg/mL (4.23 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.41 mM)