DNL 758, DNL758, DNL-758, inhibit, Eclitasertib, Inhibitor, Receptor-interacting protein kinases, SAR 443122, SAR443122, SAR-443122, RIP kinase, RIPK, RIPK1, RIPkinase
Eclitasertib is a potent small molecule RIPK1 inhibitor with an IC50 below 1 µM. It is a valuable research tool for studying necroptosis and inflammation in cellular and animal models of neurodegenerative and inflammatory diseases.