GRL-0496, CAS [[1087243-14-8]]

Product Overview

• Article Name: GRL-0496, CAS [[1087243-14-8]]
• Biozol Catalog Number: BYT-ORB1297956
• Supplier Catalog Number: orb1297956
• Alternative Catalog Number: BYT-ORB1297956-1, BYT-ORB1297956-10, BYT-ORB1297956-100, BYT-ORB1297956-2, BYT-ORB1297956-25, BYT-ORB1297956-5, BYT-ORB1297956-50, BYT-ORB1297956-500
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: SARS-CoV, SARS-CoV 3CLpro, SARS coronavirus, SARSCoV, inhibit, Inhibitor, GRL0496, GRL-0496, GRL 0496, chloropyridyl, 3CLpro

Product Description

GRL-0496 is a potent small molecule inhibitor of SARS-CoV 3CLpro, demonstrating an IC50 of 30 nM in enzymatic assays and antiviral activity with an EC50 of 6.9 µM in cellular models. It serves as a valuable research tool for studying coronavirus replication and the development of protease-targeted therapeutics in both in vitro and in vivo contexts.

Product Properties

• Molecular Weight: 272.69
• Purity: 99.90% (May vary between batches)
• CAS Number: [1087243-14-8]
• Formula: C14H9ClN2O2
• Target: SARS-CoV

Application Notes

• Application Notes: Solubility: DMSO:100 mg/mL (366.72 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (14.67 mM)