PHD-1-IN-1, CAS [[2009343-14-8]]
Catalog Number:
BYT-ORB1297970
Product Overview
Article Name:
PHD-1-IN-1, CAS [[2009343-14-8]]
Biozol Catalog Number:
BYT-ORB1297970
Supplier Catalog Number:
orb1297970
Alternative Catalog Number:
BYT-ORB1297970-1, BYT-ORB1297970-1, BYT-ORB1297970-10, BYT-ORB1297970-100, BYT-ORB1297970-200, BYT-ORB1297970-25, BYT-ORB1297970-5, BYT-ORB1297970-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
Alternative Names:
active, Arg367-out, Inhibitor, HIF, HIF ProlylHydroxylase, HIF/HIF ProlylHydroxylase, HIF Prolyl-Hydroxylase, HIF/HIF Prolyl-Hydroxylase, HIF/HIFProlylHydroxylase, HIFProlylHydroxylase, HIF-PH, HIFs, Hypoxia-inducible factors, Fe2+, inhibit, ion, iron, pocket, orally, PHD 1 IN 1, PHD1, PHD-1, PHD1IN1, PHD-1-IN-1, site
Product Description
PHD-1-IN-1 is a highly potent and selective inhibitor of the HIF prolyl hydroxylase domain 1 (PHD1) enzyme, demonstrating an IC50 of 34 nM. This compound is a valuable chemical tool for investigating hypoxia signaling pathways and has been utilized in both cellular and animal models to study ischemic and inflammatory conditions.
Product Properties
Molecular Weight:
220.23
Purity:
99.78% (May vary between batches)
CAS Number:
[2009343-14-8]
Formula:
C13H8N4
Target:
HIF/HIF Prolyl-Hydroxylase
Application Notes
Application Notes:
Solubility: DMSO:11 mg/mL (49.95 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:8 mg/mL (36.33 mM)