Compound 1T-0216 is a specific inhibitor that disrupts the AKT1-FAK protein interaction. It attenuates extracellular stress-induced FAK phosphorylation in SW620 colon cancer cells in vitro while leaving basal phosphorylation unaffected, making it a useful probe for studying FAK-related signaling in cancer cell migration and invasion research.
Molecular Weight:
397.38
Purity:
99.90% (May vary between batches)
CAS Number:
[383147-88-4]
Formula:
C20H19N3O6
Target:
Others
Application Notes:
Solubility: DMSO:25 mg/mL (62.91 mM)
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