Niraparib tosylate monohyrate, CAS [[1613220-15-7]]

Product Overview

• Article Name: Niraparib tosylate monohyrate, CAS [[1613220-15-7]]
• Biozol Catalog Number: BYT-ORB1298065
• Supplier Catalog Number: orb1298065
• Alternative Catalog Number: BYT-ORB1298065-1, BYT-ORB1298065-10, BYT-ORB1298065-100, BYT-ORB1298065-200, BYT-ORB1298065-25, BYT-ORB1298065-5, BYT-ORB1298065-50, BYT-ORB1298065-500
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Inhibitor, inhibit, MK-4827 tosylate, Niraparib tosylate, Niraparib tosylate monohyrate, orally, lung, PARP, DNA, damage, breast, anti-tumor, Apoptosis, cancer, bioavailable, poly ADP ribose polymerase, ovarian

Product Description

Niraparib (MK-4827) is a potent PARP inhibitor that disrupts the base-excision DNA repair pathway, leading to genomic instability and apoptosis in cancer cells. It is widely used in oncology research, particularly for studying BRCA-mutant cancers, and has demonstrated efficacy in both in vitro assays and in vivo tumor models.

Product Properties

• Molecular Weight: 510.61
• Purity: 99.99% (May vary between batches)
• CAS Number: [1613220-15-7]
• Formula: C26H30N4O5S
• Target: PARP,Apoptosis

Application Notes

• Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.92 mM),H2O:1 mg/mL (1.96 mM),DMSO:247.5 mg/mL (484.71 mM)